Motif ID: FOX{F1,F2,J1}.p2

Z-value: 2.159


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
Foxf1a 15227 forkhead box F1a
Foxf2 14238 forkhead box F2
Foxj1 15223 forkhead box J1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf1achr8_+_1236082520.172.1e-02Click!
Foxf2chr13_+_317176030.082.9e-01Click!
Foxj1chr11_-_1161976940.064.0e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_104542598 113.295 Sparcl1
SPARC-like 1
chr5_-_104542751 91.210 Sparcl1
SPARC-like 1
chr5_-_104542729 90.794 Sparcl1
SPARC-like 1
chr5_-_104542641 88.504 Sparcl1
SPARC-like 1
chr15_+_91958558 74.364 NM_007727
Cntn1
contactin 1
chr16_-_34263047 61.502 Kalrn
kalirin, RhoGEF kinase
chr16_-_34263272 59.566 Kalrn
kalirin, RhoGEF kinase
chr14_-_52533114 56.817 NM_001145959
NM_013864
Ndrg2

N-myc downstream regulated gene 2

chr14_-_52533039 56.605 Ndrg2
N-myc downstream regulated gene 2
chr14_-_52532988 53.878 Ndrg2
N-myc downstream regulated gene 2
chr1_-_89470442 45.015 NM_001111314
Ngef
neuronal guanine nucleotide exchange factor
chr5_+_89012596 41.641 NM_027530
Rufy3
RUN and FYVE domain containing 3
chr12_-_85791928 37.865 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr17_-_85461840 37.247 Prepl
prolyl endopeptidase-like
chr7_-_107805365 37.235 Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr5_+_89012537 37.007 Rufy3
RUN and FYVE domain containing 3
chr15_+_91991704 35.451 NM_001159647
Cntn1
contactin 1
chr2_+_71892681 33.985 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_28689289 33.481 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr12_-_85791897 33.281 NM_134042
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
5.82 1.03e-02 GO:0061041 regulation of wound healing
4.52 8.83e-03 GO:0043270 positive regulation of ion transport
3.07 2.58e-02 GO:0050878 regulation of body fluid levels
2.36 3.54e-03 GO:0051050 positive regulation of transport
1.94 1.81e-03 GO:0051049 regulation of transport
1.90 6.07e-05 GO:0032879 regulation of localization
1.48 3.24e-04 GO:0051234 establishment of localization
1.45 1.32e-03 GO:0006810 transport
1.44 1.56e-04 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
Enrichment   P-value GO Accession GO Term
2.13 4.68e-02 GO:0005792 microsome
2.10 6.85e-06 GO:0005615 extracellular space
1.97 9.91e-06 GO:0005624 membrane fraction
1.96 6.22e-06 GO:0005626 insoluble fraction
1.90 4.81e-07 GO:0000267 cell fraction
1.81 2.39e-04 GO:0044421 extracellular region part
1.68 8.61e-03 GO:0005794 Golgi apparatus
1.67 1.03e-03 GO:0031090 organelle membrane
1.39 4.86e-05 GO:0071944 cell periphery
1.36 3.42e-04 GO:0005886 plasma membrane
1.35 2.69e-07 GO:0044444 cytoplasmic part
1.22 8.62e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
11.65 2.34e-03 GO:0015248 sterol transporter activity
11.65 2.34e-03 GO:0017127 cholesterol transporter activity
4.27 2.19e-02 GO:0005496 steroid binding
2.78 2.76e-02 GO:0004866 endopeptidase inhibitor activity
2.68 4.57e-02 GO:0061135 endopeptidase regulator activity
2.29 7.20e-04 GO:0008289 lipid binding
1.63 1.93e-02 GO:0005215 transporter activity